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It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain.mbulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

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Signs and symptoms of toxicity develop rapidly after tricyclic antidepressant overdose, therefore, hospital monitoring is required as soon as possible.MJ case reports.

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Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions.Patients with cardiovascular disorders should be watched closely. Tricyclic antidepressant drugs, particularly when given in high doses, have been reported to produce arrhythmias, sinus tachycardia and prolongation of conduction time.

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Amitriptyline can amitriptyline tablet for pain relief the seizure threshold, so let your veterinarian know about any history of seizures or if any seizures occur while your pet is taking amitriptyline.

The most common adverse effects seen with amitriptyline in dogs include sedation, constipation, and urinary retention.If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.

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