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For the treatment of traveler s diarrhea due to susceptible strains of enterotoxigenic E. coli. Sulfamethoxazole and trimethoprim is contraindicated in sulfamethoxazole trimethoprim pills with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.Exceptional use for PCP prophylaxis.

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