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times the estimated maximum clinical topical dose from ELOCON Cream on a mcg/m2 basis In an oral study, mometasone furoate increased resorptions and caused cleft palate and/or head malformations hydrocephaly and domed head at 700 mcg/kg.
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Similar effects were not observed at 7. mcg/kg.The mechanism of the anti- inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids proteins, collectively called lipocortins.
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