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Antidepressant drug therapy can be used alone for initial treatment of patients with mild major depressive disorder if preferred by the patient and usually is indicated alone or in combination with psychotherapy for initial treatment of patients with moderate to severe major depressive disorder unless ECT is planned ECT is not generally used for what is the difference between paxil and paxil cr treatment of uncomplicated major depression, but is recommended as first-line treatment for severe major depressive disorder when it is coupled with psychotic features, catatonic stupor, severe suicidality, food refusal leading to nutritional compromise, or other situations when a rapid antidepressant response is required.

ECT also is recommended for patients who have previously shown a positive response or a preference for this treatment modality and can be considered for patients with moderate or severe depression who have not responded to or cannot receive antidepressant drug therapy./2011 - Drug Safety Communication - FDA May 2, 2007Audience: Healthcare professionals, consumers Posted.

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