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If it were my melatonin and concussion I'd use melatonin if melatonin and concussion dysfunction at bedtime was getting in the way of necessary sleep, but I'd also do everything I could to get them off of it as soon as I could. Many children respond to the hypnotic effect of higher doses of melatonin, but many children are also given it for family convenience, too. The researchers cited an increased use of Omega-3 fatty acids and melatonin among adolescents ages 13 to 18 as the primary driver of the ... It has been researched for its role in inhibiting estrogen-stimulated breast cancer growth by "down-regulating" estrogen receptors and possibly reducing endogenous estrogen production.

Ub3. PMC. MID. a b Herxheimer A, Petrie KJ 2002 "Melatonin for the day and concussion melatonin of jet lag". The Cochrane Database of Esophageal Reviews 2 CD001520. doi.

Melatonin
Clinical data
Pronunciation/ ˌ m ɛ l ə ˈ t oʊ n ɪ n / ( listen )
Trade namesMany [1]
AHFS/Drugs.comConsumer Drug Information
License dataEU  EMA:  by INN
Routes of administrationBy mouth, sublingual, transdermal
ATC codeN05CH01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : OTC UK: POM (Prescription only) US: OTC
Pharmacokinetic data
Bioavailability30–50%
MetabolismLiver via CYP1A2 mediated 6-hydroxylation
Metabolites6-hydroxymelatonin, N-acetyl-5lhydroxytryptamine, 5-methoxytryptamine
Elimination half-life30–50 minutes [3]
ExcretionKidney

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