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Severe Tissue Injury, Including GangrenePromethazine hydrochloride injection can cause how to get promethazine codeine syrup prescribed chemical irritation and damage to tissues regardless of the route of administration. Irritation and damage can result from perivascular extravasation, unintentional intra-arterial injection, and intraneuronal or perineuronal infiltration.Pyridoxine may be more effective than placebo at reducing nausea but we don't know about vomiting, and evidence was weak.

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