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Than in the TMZ MR 35-mg group 19 patients. n the TMZ MR 80-mg group, the most frequently reported EAE at least two patients was influenza two patients whereas in the TMZ MR 35-mg group it was hyperglycemia four patients hyperbilirubinemia two patients and atrial vastarel mr 80 mg nedir two patients No EAE led to dose modification, withdrawal, or temporary interruption of the study treatments.High fatty acid oxidation rates are detrimental during ischemia due to an inhibition of glucose oxidation leading to uncoupling of glycolysis and an increase in proton production, which has the potential to accelerate sodium and calcium overload in the heart, which leads to an exacerbation of ischemic injury and decreased cardiac efficiency during reperfusion.

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